Board of Directors
President of CET, Michael was graduated from Columbia University and received his doctoral degree in physiological psychology from Brown University in 1968. He is Professor of Clinical Psychology in Psychiatry at Columbia, and Director of the Comprehensive Chronotherapy Group, a clinical consortium that provides multifactor assessment and treatment by specialists in chronotherapy, psychopharmacology, and psychotherapy. The group supervises patients in home treatment nationwide
For the first part of his career, Michael concentrated on laboratory studies of biological rhythms and sensory perception in animals, especially their reactions to daily cycles of light and darkness. In the early 1980’s, when such effects were first demonstrated in humans, he turned in the clinical direction, with studies of the antidepressant effects of light therapy, sponsored by the National Institute of Mental Health. He joined the faculty of Columbia’s College of Physicians and Surgeons and New York Psychiatric Institute, where he established the Clinical Chronobiology and Winter Depression Programs, in which several hundred patients have participated in treatment trials and studies of physiological responses.
This work led to a set of new non-drug therapies including 10,000 lux light, dawn/dusk simulation and high-density negative air ionization. In 1988, he was a co-founder with Anna Wirz-Justice of the Society for Light Treatment and Biological Rhythms (SLTBR), which he served as President (1991-93). He founded CET in 1994.
Michael chaired the Task Force on Light Treatment for Sleep Disorders (American Academy of Sleep Medicine and SLTBR), and served for 12 years on the editorial board of the Journal of Biological Rhythms. In a 40-year collaboration with his wife, Jiuan Su, the Terman lab has produced more than 200 scientific publications.
His co-authored clinicians’ manual, Chronotherapeutics for Affective Disorders, was issued in a second edition in 2013, as was his book for general readership, Reset Your Inner Clock. Beyond books, Michael reaches out to the public with information about chronotherapy via Twitter, Facebook, and Psychology Today.
José Balido graduated magna cum laude from Georgetown University’s School of Languages and Linguistics with a Bachelor of Science in Chinese and a minor in linguistics. Also fluent in Spanish, French and Italian, he honed his skills as a writer and editor in different media, ranging from daytime television to top travel magazines. Currently a public relations professional and social media specialist with Tinkle Communications of Madrid overseeing a multinational and multilingual team, he helps clients communicate and engage with their audiences on multiple platforms. He is also owner of travel social network Tripatini.com, which the New York Post dubbed “Facebook for travelers.”
Having overcome Seasonal Affective Disorder under Dr. Terman’s guidance, José has committed to helping raise awareness of the benefits of chronotherapy, knowing full well the difference it made in his own life.
Dr. Namni Goel is a Research Associate Professor of Psychology in the Department of Psychiatry at the University of Pennsylvania Perelman School of Medicine. Dr. Goel received her BA in Psychology and Anthropology from the University of California, Berkeley and her PhD in Biological Psychology from the University of Michigan (Ann Arbor). As a graduate student, she researched the behavioral and neuroanatomical substrates underlying circadian rhythms in an animal model. As a postdoctoral fellow at Columbia and Cornell Universities, Dr. Goel made the transition to human work, conducting studies on basic human physiological sleep and on seasonal affective disorder (SAD), a mood disorder which may result from circadian rhythm pathophysiology.
For the past 15 years, as a behavioral neuroscientist, Dr. Goel has been conducting research in the fields of circadian rhythm physiology, chronobiological treatments and mood, and sleep-wake functions in both human and animal models. Most recently, Dr. Goel has conducted studies of candidate circadian and non-circadian genes for sleep homeostasis and human neurobehavioral vulnerability to sleep deprivation and physiological and neurobehavioral experimental studies of sleep deprivation in healthy adults. Dr. Goel has over 50 scientific publications in these areas of research.
Dr. Goel has obtained prior funding from NIH, and she is currently the Principal Investigator of a major 5-year Department of Defense grant investigating candidate genes for sleep homeostasis and human neurobehavioral vulnerability to sleep deprivation. She is also Co-Investigator on a number of other grants from NSBRI and NIH.
Dr. Goel served from 2008-2010 as President of the Society for Light Treatment and Biological Rhythms (SLTBR). Dr. Goel is an Academic Editor for PLoS ONE, an Associate Editor for SLEEP, and a Review Editor for Frontiers in Behavioral and Psychiatric Genetics. She also serves on the Editorial Boards of four other journals (Chronobiology International, Journal of Circadian Rhythms, Journal of Neurology Research, and Journal of Sleep Disorders: Treatment and Care). She is a member of the Sleep Research Society, the Society for Research on Biological Rhythms and the Society for Neuroscience, is Co-Chair of the Neurobehavioral and Psychosocial Factors Workgroup for the NASA Decadal Review of the Role of Sex/Gender in Adaptation to Spaceflight, and is an ad hoc member of NIH Study Sections F02B and MESH.
Dr. John Gottlieb received his undergraduate degree from Oberlin College, attended medical school at the University of Illinois at Chicago, and completed a residency in psychiatry at Yale University in New Haven, Connecticut.
He is an Assistant Professor of Psychiatry at the Feinberg School of Medicine of Northwestern University in Chicago, Illinois. In his university position, John has been actively involved in residency education and supervision. In this role, he developed and teaches one of the first courses in psychiatric chronotherapy in the United States.
In addition, he is the Medical Director of Chicago Psychiatry Associates, a group practice specializing in the evaluation and treatment of cyclic mood disorders. He is a member of the Training and Curriculum Committee of the International Society for Bipolar Disorders.
John’s clinical focus on bipolar disorders led to his interest in both the circadian underpinnings of affective disturbances and the use of biological rhythm-modifying interventions to treat these conditions. He regularly uses bright light therapy, dawn simulation, wake therapy, and darkness therapy.
John’s current research focus is on circadian phase variation in bipolar illness and the use of darkness therapy for manic symptoms.
Paul Kallmes, our technical advisor, consults with CET on technology and product research and development. He has held numerous positions with prominent companies in the lighting industry, including Color Kinetics and Lighting Science Group; he has also advised many other lighting companies on their intellectual property and product development strategies. He is currently raising a venture fund to drive the growth of young companies in the biotech, security, wearables, and cosmetics spaces. Paul serves on the boards of two non-profits: one based in San Francisco that concentrates on technology and education, and one focusing on teaching low-cost, high-volume, quality eye surgery to Chinese ophthalmologists.
Dr. Dan Oren received the MD degree from the Yale School of Medicine, where he later did his training in psychiatry and served as an Associate Professor of Psychiatry. He is Medical Director at BHcare in Ansonia, Connecticut, USA.
Dan’s research and clinical interests grew out of a research fellowship in the Clinical Psychobiology Branch of the US National Institute of Mental Health (NIMH) where he worked under the guidance of Drs. Thomas Wehr and Norman Rosenthal, two of the pioneer generation of researchers in the rediscovery and classification of Seasonal Affective Disorder and the establishment of light therapy as a treatment for depression.
His interests include seasonal, atypical, chronic and resistant depression, clinical psychopharmacology, light therapy, sleep disorders and circadian rhythm disturbances. He has written numerous scientific articles and book chapters, and is lead author of How to Beat Jet Lag: A Practical Guide for Air Travelers. His research passion is understanding the molecular mechanism of light therapy for treatment of depression and regulation of biological rhythms, for which he proposed a model of “humoral phototransduction” to explain these phenomena on a molecular level.
Dan is a former president of the Society for Light Treatment and Biological Rhythms. Dan serves as Medical Director of CET’s Chronotherapeutics Consultants, formed in 2004 to advise the hospital and managed care industries on the implementation of light and wake therapies as adjuncts to drug treatment of major depression.
Marylou Selo was born in Bolivia, grew up in Holland and studied in Geneva, Switzerland, and at Georgetown University in Washington, D.C. There she obtained her Diploma as Conference Interpreter and Translator for Dutch, German, English, French, and Spanish. Since 1963, her main home has been New York City.
Marylou was diagnosed with bipolar disorder in 1976, and told she would never work again. Despite this dire prognosis, she quickly resumed her career as a freelance interpreter. She also became a patient advocate in the United States and Europe. She is a co-founder of the Mood Disorder Support Group of New York, Inc, and of the national DBSA (Depression and Bipolar Support Alliance, then known as the National Depressive and Manic Depressive Association). She served as a Board Member of both organizations.
Following the suicide of her father in 1993, Marylou became active in suicide prevention and the destigmatization of mental illness. She served as a Board Member of BBRF (Brain and Behavior Research Foundation), previously NARSAD (National Alliance for Research in Schizophrenia and Affective Disorders), and supported brain research.
In 1994 she founded the Werner Alfred Selo Foundation in Zug, Switzerland, to support research on the comorbidity of depression and headaches. With a group of fellow patients she founded Equilibrium, the Self-Help Organization in Switzerland.
In 2006 Mogens Schou made Marylou the “Poster Child” of IGSLI (International Group for the Study of Lithium), which he had founded to promote the use of lithium.
In 1997 several patient organizations came together in Venice and founded GAMIAN (Global Alliance of Mentally Ill Advocacy Networks). Marylou briefly served as President of GAMIAN-Europe.
Marylou also represents Switzerland at the European Depression Association in Brussels, Belgium. This organization coordinates the activities for European Depression Day (October 1) in all of Europe.
She is a member of the International Bipolar Society and the bipolar societies of Switzerland, Austria and Germany. She advocates for patients’ rights, visits self-help groups, writes for various German newsletters, and lectures at continuing education classes for general practitioners. She also answers e-mail from patients and family members who contact her directly.
Marylou, along with Kay Redfield Jamison, and two other individuals, were featured in a Swiss docudrama, Bipolar ― Life Between Two Extremes. Marylou also appears in Depression: Voices of an Illness, a documentary on depression directed by Bill Liechtenstein.
Anna Wirz-Justice, PhD, is a neurobiologist and emerita Professor at the Centre for Chronobiology, Psychiatric Clinics of the University of Basel.
The Basel clinic was one of the first to extensively study the antidepressant effects of sleep deprivation in the early 70’s. During a fellowship at the US National Institute of Mental Health, she and Thomas Wehr, MD, carried out the first sleep phase advance experiment in a bipolar patient. Anna introduced light therapy to Europe, and followed up with more than 20 years of research on Seasonal Affective Disorder and the psychobiological effects of light. In recent years actimetry studies of rest-activity cycles in psychiatric patients has demonstrated circadian dysregulation in a wide variety of disorders that might be amenable to improvement with light therapy (eg, borderline personality disorder, depression during pregnancy, schizophrenia).
Anna is a former president of the Society for Light Treatment and Biological Rhythms. A prestigious Anna-Monika-Prize with Thomas Wehr recognized their seminal work in the chronobiology of depressive illness. In 2002, she received the Scholar’s Prize of the City of Basel, awarded for outstanding scientific career achievement. In a thematically relevant avocation, she has interacted with architects to enhance the circadian impact of indoor lighting, and the first applications of chronobiological principles are being developed for retirement homes, living quarters for patients with dementia.
Anna is director of CET’s Chronotherapeutics Consultants, formed in 2004 to advise psychiatrists on the implementation of light and wake therapies as adjuncts to drug treatment of major depression. She led a team including Francesco Benedetti and Michael Terman to the field’s first treatment manual for clinicians, Chronotherapeutics for Affective Disorders, now in its second edition. Most recently, together with colleagues, she has been developing courses in chronotherapy to better apply what we know in everyday clinical practice.
CET Board of Advisors
Francesco Benedetti, MD (University of Modena, 1991) is Head of the Psychiatry and Clinical Neurosciences research group at the San Raffaele Hospital in Milano, and contract professor of Psychiatry and of General Psychopathology at the University Vita-Salute San Raffaele.
His clinical research group gathers researchers working at the interface between neuroscience and behavioral disorders. Areas of expertise encompass clinical psychobiology, brain imaging, genetics of response to psychiatric treatments, pharmacology, neuropsychology, neurophysiology, and genetic correlates of psychopathological conditions.
In the last 15 years he and his group have developed clinical chronotherapeutics of mood disorders into a practical, everyday method for the psychiatric ward, particularly focusing on bipolar disorder. Beginning with sleep deprivation, they added sleep phase advance, light therapy, and different medications to see if the rapid response could be maintained. They found that the same gene polymorphisms that hinder clinical response to antidepressants affect the response to chronotherapeutics in a similar fashion. At the functional MRI level, those selective regions of the brain that are modified by improvement on antidepressants also are the ones involved in chronotherapeutic response. These multiple approaches provide an important scientific database to document efficacy and mechanisms of action of non-pharmacological antidepressant methods.
Francesco is a member of CET’s Chronotherapeutics Consultants, and was the major clinical expert in writing our treatment manual, Chronotherapeutics for Affective Disorders.
Konstantin V. Danilenko
Konstantin V. Danilenko, MD, is a biomedical researcher, and a vice director for scientific and clinical research at the Institute of Physiology, Siberian Branch of the Russian Academy of Medical Sciences, Novosibirsk, Russia.
His research focuses on the light physiology in humans. He has conducted a series of fundamental and clinical studies on retinal sensitivity, biological clock and melatonin secretion, winter depression and reproductive function, with support from colleagues from abroad and international grants.
He has been a member of the Society for Light Treatment and Biological Rhythms (SLTBR) since 1989.
Claude Gronfier received his PhD in neuroscience from the University Louis Pasteur (Strasbourg, France) in 1998. During a fellowship at Harvard Medical School, he studied the consequences of having an internal biological clock improperly reset by light, and how to maintain synchrony with the light-dark cycle in extreme conditions such as spaceflight.
In 2003, he joined an Inserm laboratory (French National Institute of Health and Biomedical Research) as Chargé de Recherche (Senior Research Associate). His current projects focus on light’s mechanisms of action on the biological clock, and sleep disorders in conditions such as ocular pathology, neurodegenerative disease, aging and mood disorders.
He is a board member of the French Society of Research and Sleep Medicine and the Society for Light Treatment and Biological Rhythms, and he serves on two technical committees of the Commission Internationale de l’Eclairage (CIE TC 6-62 and TC 6-63).
Claude is co-author of the recent book for the French public, En finir avec le blues de l’hiver et les troubles du rythme veille-sommeil (Marabout, 2008).
Director of the Built Environment
Markus Haberstroh studied architecture at the University of Applied Sciences in Aargau, Switzerland, graduating in 2001. From 2001 to 2004 he worked with Herzog & de Meuron Basel as Project Manager on projects and competitions in Europe. In 2005 he performed his civil service at the Center for Chronobiology in Basel where he became acquainted with the connection between architecture and chronobiology. During his civil service, he designed and constructed the website of the Center for Chronobiology Basel, as well as CET’s website. In 2009, Markus established his own architectural practice in Basel. With the knowledge of both fields, he directs CET’s Architecture Initiative, representing CET’s mission and values in building projects. One of his main goals is to analyze the literature and standards in contemporary architecture to integrate the chronobiological vantage point and create better projects for the end user.
Farhad Hafezi, MD, PhD, is a corneal and refractive laser surgeon specialized in complication management. Prof. Hafezi is also one of the pioneers of the collagen cross-linking (CXL) treatment method for keratoconus and postoperative ectasia. His research focuses on corneal biomechanics, and CXL; his most recent publications involve the novel method for treating corneal infections using CXL parameters called PACK-CXL (Photo-Activated Chromophore for Keratitis).
Philantrophically, Prof. Hafezi founded an initiative called Light for Sight to eliminate preventable blindness among children and adolescents with keratoconus.
In 2010, Professor Hafezi was appointed Chair and Prof. of Ophthalmology of the University Eye Clinic of Geneva and Eye Clinic Director at the Geneva University Hospitals in Switzerland. In 2012, the faculty of the Keck School of Medicine at the University of Southern California (USC) Los Angeles (Doheny Eye Institute) appointed Professor Hafezi as Clinical Professor of Ophthalmology.
In 2013, Prof. Hafezi was a co-founder and head scientific advisor of the spin-off company from the University of Geneva called EMAGine SA (Zug, Switzerland). This company will bring out the first device to treat corneal infections at the slit lamp using CXL technology.
Prof. Hafezi has published 130 articles and book chapters including articles in Nature Medicine, Nature Genetics and Genes & Development. His work has been cited more than 3,600 times with a total impact factor of 356 (ISI 2012) and h index of 33.
Robert D. Levitan, M.D., is a Psychiatrist at the Centre for Addiction and Mental Health, and a Professor of Psychiatry and Physiology at the University of Toronto, Toronto, Canada. Robert’s primary interest is the “atypical spectrum” of mood disorders which encompass both depression and overeating/obesity, including seasonal affective disorder (SAD). He studies the early developmental origins of these disorders, and the use of light therapy for various disorders that can be influenced by seasonal effects, including attention deficit disorder. The use of light therapy to phase advance delayed circadian rhythms in these patients is a particular focus of this work.
Klaus Martiny, MD, PhD, Specialist in Psychiatry, works as head of an intensive affective disorders unit, and as researcher at the Mental Health Center Copenhagen, University Hospitals of Copenhagen. His main research interest has been focused on augmentation strategies as add-ons to psychopharmacologic treatment for depression. His studies have included the use of bright light therapy, pindolol, weak electromagnetic fields, wake therapy in combination with sleep time stabilization and bright light therapy, and exercise. He is presently also doing chronobiological research of diurnal variation in depression, with a multilevel assessment of brain functioning, biomarkers and psychopathology.
Dr. Martiny is the immediate Past President of CETs affiliate, the Society for Light Treatment and Biological Rhythms.
Trained in electrical controls and instrumentation, Paul Riccobono is the founder and president of Complete Control Solutions LLC. This electrical and mechanical control consulting firm focuses in the highly specialized area of design for environmental, electrical and mechanical control systems in nontraditional spaces. His designs have been implemented in many high-end retail stores, and New York City landmarks including Grand Central Terminal. Paul has worked with CET on high density negative air ionization since 2010.
Dorothy Sit, MD, is an Assistant Professor of Psychiatry at the University of Pittsburgh, Western Psychiatric Institute and Clinic. Her research focus is on novel treatment development for patients with Bipolar Disorder (BD). She recently completed a randomized control trial to examine the efficacy of light therapy for the treatment of bipolar depression. She is investigating possible changes in chronobiological rhythms (sleep, melatonin, activity levels) from light therapy in depressed patients with BD. She is launching new studies to explore early visual processing, and visual and neural markers of light therapy, in BD to examine putative novel predictors of treatment response and to further investigate the pathophysiology underlying BD. Her research also extends to the study of the phenomenology, psychopharmacology and metabolism of women with BD and Major Depressive Disorder across the life cycle (pregnancy, postpartum, menstrual cycles).
Dr. Joseph Wu has done studies on chronobiological manipulations focused on mood elevation in depressive disorders using sleep deprivation (aka “wake therapy”), sleep phase advance, and bright light treatment. He demonstrated a robust improvement above and beyond medication treatment as usual approaches that indicated not only did depressed patients respond more quickly to the chronobiological treatment but also had much greater final antidepressant effect. He has also done brain imaging studies on how the brain changes in response to chronobiological interventions, such as sleep deprivation, and demonstrated a key role for the subgenual region of the anterior cingulate.
Psychologist Elizabeth Saenger received a PhD from Harvard University, and completed her postdoctoral work at the University of California at Berkeley. Subsequently, she taught and worked off and on at Columbia University, where she met Dr. Michael Terman. As a clinician, Dr. Saenger specialized in mood disorders, and in helping people help themselves. As editorial director of psychiatry for Medscape, LLC, of WebMD, she developed content on the diagnosis and treatment of many disorders, as well as online continuing medical education on recovery, empowerment, stigma, seclusion and restraint, and medical error. Dr. Saenger writes for both the public, and clinicians, on depression, bipolar disorder, negotiation, relationships, and other topics. She serves as Director of Education at CET.
Nikki L. K. Hafezi
Nikki Hafezi serves as Development Associate for CET, and administrative coordinator for CET’s affiliate, the Society for Light Treatment and Biological Rhythms.
Mrs. Hafezi received her bachelor’s degree from UCLA and earned her master’s degree in intellectual property at the Swiss Federal Institute of Technology in Zurich (ETH). She resides with her husband and three daughters in Baar, Switzerland.